2015-2021年CHINET临床分离不动杆菌属细菌耐药性变迁

CHEN Jiawei,XU Yingchun,TONG Dawei, YANG Yang,HU Fupin,ZHU Demei, LI Hui,JI Ping,XIE Yi,KANG Mei,WANG Chuanqing, FU Pan,XU Yuanhong,HUANG Ying,SUN Ziyong,CHEN Zhongju,NI Yuxing,SUN Jingyong,CHU Yunzhuo,TIAN Sufei,HU Zhidong,LI Jin,YU Yunsong,LIN Jie,SHAN Bin,DU Yan,GUO Sufang,WEI Lianhua,ZOU Fengmei,ZHANG Hong,WANG Chun,HU Yunjian,AI Xiaoman,ZHUO Chao,SU Danhong,GUO Dawen,ZHAO Jinying,YU Hua,HUANG Xiangning, LIU Wen'en,LI Yanming,JIN Yan,SHAO Chunhong,XU Xuesong,YAN Chao,WANG Shanmei,CHU Yafei,ZHANG Lixia,MA Juan,ZHOU Shuping,ZHOU Yan,ZHU Lei,MENG Jinhua,DONG Fang,LÜ Zhiyong,HU Fangfang,SHEN Han,ZHOU Wanqing,JIA Wei,LI Gang,WU Jinsong,LU Yuemei,LI Jihong,DUAN Jinju,KANG Jianbang,MA Xiaobo,ZHENG Yanping,GUO Ruyi,ZHU Yan,CHEN Yunsheng,MENG Qing,WANG Shifu,HU Xuefei,SHEN Jilu,WANG Ruizhong,FANG Hua,YU Bixia,ZHAO Yong,GONG Ping,WEN Kaizhen,ZHANG Yirong,LIU Jiangshan,LIAO Longfeng,GU Hongqin,JIANG Lin,HE Wen,XUE Shunhong,FENG Jiao,YUE Chunlei

Chinese Journal of Infection and Chemotherapy（2023）

引用 0|浏览1

暂无评分

摘要

目的了解2015-2021年我国不同地区51家医院分离的不动杆菌属分布情况和耐药变迁趋势.方法按CHINET耐药监测方案,采用纸片扩散法或自动化仪器法对收集的菌株进行药敏试验,按CLSI 2021 年版标准判读药敏结果,采用WHONET 5.6 软件进行数据分析.结果在此期间共分离到不动杆菌属 143 393 株,其中鲍曼不动杆菌是最常见的菌种,占所有不动杆菌属的 89.6%.呼吸道样本分离最常见的是不动杆菌属,占所有样本分离株的 73.0%.94.0%的菌株分离自住院患者,其中ICU分离的菌株占 35.5%.除米诺环素、替加环素和多黏菌素B外,不动杆菌属对其他抗菌药物如β内酰胺类、氨基糖苷类和氟喹诺酮类等耐药率较高.不同等级医院和不同科室分离的不动杆菌属对抗菌药物的耐药率存在差异.2015-2021 年鲍曼不动杆菌对头孢哌酮-舒巴坦和哌拉西林-他唑巴坦耐药率呈现上升趋势,而对替加环素和米诺环素的耐药率呈现下降趋势.碳青霉烯类耐药的鲍曼不动杆菌分离率较高,在三级医院达75.2%.结论不动杆菌属是医院感染的重要病原菌,对临床常用抗菌药物呈现较高的耐药性.对于多重耐药不动杆菌属感染,可以采用多黏菌素B、替加环素和米诺环素等抗菌药物治疗.

关键词

Acinetobacter spp,antimicrobial resistance surveillance,carbapenem-resistant Acinetobacter baumannii

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要