靶向GPC3的CAR-T细胞治疗肝癌研究进展
Journal of Guangxi Medical University（2023）
Abstract
嵌合抗原受体T细胞(CAR-T)是治疗肿瘤的新型免疫疗法,磷脂酰肌醇蛋白聚糖3(GPC3)在肝癌(HCC)组织中高表达,是治疗HCC的理想靶标,靶向GPC3的CAT-T细胞治疗HCC效果显著,被认为是最具潜力的免疫疗法之一.本文对靶向GPC3 CAR-T细胞治疗HCC的最新研究进展进行综述.
MoreKey words
chimeric antigen receptor T cell,hepatocellular carcinoma,nanobody,Glypican-3,solid tumor
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