Side effects of diuretics

The purpose of this chapter is to review the adverse effects associated with diuretics. A literature search using PubMed, Medline, and Cochrane (January 2022–December 2022) was performed utilizing keywords: pamabrom, acetazolamide, methazolamide, bumetanide, ethacrynic acid, furosemide, Furoscix, torsemide, mannitol, amiloride, triamterene, eplerenone, spironolactone, hydrochlorothiazide, chlorthalidone, chlorothiazide, methylclothiazide, bendroflumethiazide, indapamide, metolazone, diuretics, adverse effects, and side effects. All English-language reports during the specified year were included for this review. Adverse effects were reported for the following medications: eplerenone, spironolactone, acetazolamide, methazolamide, bumetanide, furosemide, and hydrochlorothiazide. This chapter outlines the findings from the identified articles including adverse effects, suspected mechanisms underlying these effects, and implications to clinical practice and patient care.