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Protective Effect of Pituitary Adenylate Cyclase-Activating Polypeptide-38 Against Radiation-Induced Myocardial Injury in Mice

Huan Li,Peiqiang Yi,Qian Zhu,Lei Cao,Cheng Xu,Min Li,Jiayi Chen

Cardiology and cardiovascular medicine（2023）

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Abstract
Background: Radiation-Induced Heart Disease (RIHD) restricts the survival benefit of radiotherapy for thoracic tumors. Myocardial fibrosis and remodeling are late consequences of the long-term development of RIHD, and pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) could ameliorate RIHD.
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Key words
protective effect,cyclase-activating,radiation-induced
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