Front Cover Picture: Oxidative Annulation of Aldehydes, 5‐Aminopyrazoles, and Nitriles: Synthesis and Applications of Pyrazolo[3,4‐d]Pyrimidines (Adv. Synth. Catal. 8/2023)

The front cover illustrates an oxidative annulation reaction of aldehydes, 5-aminopyrazoles, and nitriles achieved under the oxidation of I2/O2. The theme picture of “Monkey king stealing elixirs” (from “Journey to the West”) was used to represent the one-pot generation of valuable pyrazolo[3,4-d]pyrimidine products that light up lipid droplets in living cells, similar to the piercing eyes gained after the Monkey king ingested the elixir. Details can be found in the Research Article by Hanhong Xu, Chuanle Zhu and co-workers (G. Yao, C. Zhu, T. Qin, M. Wang, Z. Sun, R.-Y. Tang, C. Zhao, H. Jiang, H. Xu, Adv. Synth. Catal. 2023, 365, XXXX–XXXX; DOI: 10.1002/adsc.202201212)