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An 19f Nmr Fragment-Based Approach for the Discovery and Development of Brca2-Rad51 Inhibitors to Pursuit Synthetic Lethality in Combination with Parp Inhibition in Pancreatic Cancer

Samuel H. Myers,Laura Poppi,Francesco Rinaldi,Marina Veronesi,Andrea Ciamarone,Viola Previtali,Greta Bagnolini,Fabrizio Schipani, Jose Antonio Ortega Martinez,Stefania Girotto,Giuseppina Di Stefano,Fulvia Farabegoli,Naomi Walsh,Francesca De Franco,Marinella Roberti,Andrea Cavalli

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

引用 3|浏览6
关键词
Synthetic lethality,BRCA2-RAD51,PARP inhibition,NMR fragment-based screening,Pancreatic cancer
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