A multiplatform metabolomics approach for comprehensive analysis of GIST xenografts with various KIT mutations

Szymon Macioszek,Danuta Dudzik, Margot Biesemans,Agnieszka Woźniak,Patrick Schöffski,Michał J. Markuszewski

Analyst（2023）

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摘要

Metabolomics is a promising tool for studying the impact of mutations or treatments on GIST tissue. We found that parallel GC-MS and RP-LC-MS analyses allow one to obtain a comprehensive global picture of the GIST metabolome.

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关键词

multiplatform metabolomics approach,gist xenografts,mutations

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