Methylation/molecular Profiling to Aid in Diagnosis and Radiation Treatment for an Intracranial Ewing's Sarcoma in a Pediatric Patient: A Case Report.

Central nervous system (CNS) tumors have a high mortality rate and often pose a diagnostic challenge because of their heterogeneity and the presence of variable pluripotent or differentiated cell types. Among primary pediatric CNS tumors, undifferentiated small blue round cell tumors are frequently observed, encompassing a variety of tumor types. The availability of molecular characterization, including genomic and epigenomic characterization, helps in the diagnosis of these tumors.1,2