Musculoskeletal and Somatic Manifestations of Haematological Disease: A Review of the Spectrum of Disease from a Tertiary Academic Hospital in Johannesburg, South Africa

The complexity of the musculoskeletal and rheumatologic manifestations of hematologic disease, both benign and malignancy-associated haematologic disease, is extensively explored in this accompanying review article. Accompanying reference to unique radiological images in this review aids in understanding the importance and effect of hematological disease on patient quality of life. This review implores the understanding of the “immune-skeletal interface” as the unique basis of osteoimmunology, as well as descriptively accounting for avenues of bone health to be observed when treating the patient with hematologic disease.