Frontispiece: Spatiotemporal single‐cell transcriptomic profiling reveals inflammatory cell states in a mouse model of diffuse alveolar damage (EXP2 3/2023)

Exploration(2023)

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Abstract
This study presents a comprehensive cellular atlas describing the ongoing pulmonary immune responses in the early stages of diffuse alveolar damage. This work indicates a vital role of the hyper-inflammatory fibroblast subset around the bronchus, in mediating neutrophil infiltration through secreting soluble signaling mediators, thus boosting neutrophilic airway inflammation.
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Key words
inflammatory single‐cell states,alveolar damage,transcriptomic
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