Basicity‐Controlled [3+2] Cyclization of 3‐Hydroxyquinolin‐ones and β‐Chlorinated Nitrostyrenes

Abstract The construction of novel skeletons through the recombination of natural products ring systems is attractive. Herein, a basicity‐controlled synthesis of (dihydro)furo[2,3‐ c ]quinolin‐4(5 H )‐one derivatives through (3+2) cyclization between 3‐hydroxyquinolin‐2‐ones and β ‐chlorinated nitrostyrenes was developed. In addition, preliminary study gave the chiral dihydrofuro[2,3‐ c ]quinolin‐4(5 H )‐one derivatives with up to 83 % ee.