Rigid H₄OCTAPA derivatives as model chelators for the development of Bi(iii)-based radiopharmaceuticals

Fátima Lucio‐Martínez,David Esteban‐Gómez,Laura Valencia, D. G. Horvath,Dániel Szücs,Anikó Fekete,Dezső Szikra,Gyula Tircsó,Carlos Platas‐Iglesias

Chemical Communications（2023）

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Abstract

Non-macrocyclic H 4 OCTAPA derivatives form highly stable complexes with Bi( iii ), but require an appropriate rigid spacer to enhance the inertness of the complex, as demonstrated by radiolabeling studies with 205/206 Bi-nuclides.

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Key words

h<sub>4</sub>octapa derivatives,model chelators

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Rigid H4OCTAPA derivatives as model chelators for the development of Bi(iii)-based radiopharmaceuticals

Rigid H₄OCTAPA derivatives as model chelators for the development of Bi(iii)-based radiopharmaceuticals