Advancing Malignancy Risk Stratification for Early-Stage Cancers in Lung Nodules by Combined Imaging and Electrical Impedance Analysis

Computed tomography (CT) has been the diagnostic mainstay for lung cancer screening and has significantly reduced mortality in high-risk populations. However, malignancy risk stratification using traditional imaging technologies for lung nodules remains a clinical challenge driven by the subjective implementations of nodule management protocols given the different background and expertise of clinicians. There is an unmet need for a similarly non-invasive and objective diagnostic tool which can be used adjunctively with CT for evaluating early cancer risks in lung lesions.