Nano-encapsulation of halofuginone hydrobromide enhances anticoccidial activity against Eimeria tenella in chickens

Mengjuan Lin,Xinhao Song,Runan Zuo,Yuling Zheng,Shiheng Hu, Shasha Gao,Lu Chen, Yuan Zhu,Xiaolin Xu,Moxin Liu,Junren Zhang,Shanxiang Jiang,Dawei Guo

Biomaterials Science（2023）

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摘要

HF-loaded TPGS polymer micelles (HTPM) were developed to improve the anticoccidial effect of loaded drugs by enhancing cellular take up, denaturing merozoites inside infected cells, and restoring the gut microbiome.

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关键词

<i>eimeria tenella</i>,halofuginone hydrobromide,anticoccidial activity,nano-encapsulation

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