Identification of Candidate Neural Biomarkers of Obsessive-Compulsive Symptom Intensity and Response to Deep Brain Stimulation

Biological Psychiatry(2023)

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摘要
Despite the success of deep brain stimulation (DBS) for treatment of refractory obsessive-compulsive disorder (OCD), there are currently no robust neural signatures for obsessive-compulsive (OC) symptoms or initial mood and energy improvements often associated with DBS. This may be due to limited opportunities available for conducting intracranial electrophysiological recordings in natural environments where fluctuations in symptoms take place.
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关键词
deep brain stimulation,candidate neural biomarkers,brain stimulation,obsessive-compulsive
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