Cover Picture: A visualized automatic particle counting strategy for single‐cell level telomerase activity quantification (View 3/2023)

In article number 20220078, Ying Tan and co-workers describe a convenient visualized automatic gold nanoparticles (AuNPs) counting strategy based on dark-field microscopy (DFM) for single-cell level telomerase activity detection. In this cover, after magnetic separation and DNA double-strand unwinding, AuNPs were collected, and the telomerase activity was quantitatively measured by visually counting bright spots based on DFM. This strategy can clearly identify bladder cancer in various urinary diseases, indicating its potential for early and non-invasive diagnosis of bladder cancer.