MpMRI and [18F]PSMA-1007 PET to detect local prostate cancer: a prospective comparative study with correlation to histopathology

Bastiaan M. Privé,Bas Israël,Marcel Janssen,Patrik Zámecnik,Marloes van der Leest, Willemijn van Gemert,Martin Gotthardt, J Michiel P M Sedelaar,Jelle O. Barentsz,Inge M. van Oort,James Nagarajah

Nuklearmedizin-nuclear Medicine（2023）

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摘要

Ziel/Aim Prostate mpMRI is an effective tool to discriminate between healthy and malignant prostate tissue. However, due to the high rate of equivocal lesions and false-positive findings, mpMRI has room for improvement. This could be provided by PSMA PET. In this setting, [18F]PSMA-1007 is of particular interest due to the low renal excretion. The present study aimed to investigate the role of [18F]PSMA-1007 PET/CT following the mpMRI to aid in the detection of local prostate tumors.

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关键词

local prostate cancer,prostate cancer,mpmri,pet

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