Prevalence of yellow fever virus among lassa fever pcr negative febrille patients in nigeria

Background Yellow fever is a viral illness caused by an RNA virus from the Flavivirus genus, which is transmitted between humans and Aedes aegypti mosquitoes. Although the virus often spreads through a specific transmission method (Sylvatic Cycle), it can also cause a generally brief illness in infected individuals. Methodology The study was designed as a cross-sectional investigation that analyzed stored Lassa fever PCR negative febrile samples. Randomly, 40 samples were selected and enrolled in the study. The RT-PCR technique was employed to convert the RNA virus to a complementary RNA and subsequently amplify it. The Quagen Analysis was used to analyze the results of the FAM (yellow fever-specific RNA) and the JOE (internal control). Results After analyzing the samples, the results revealed that none of the studied samples were positive for the Yellow Fever virus. Conclusion The study concluded that there was no evidence of yellow fever transmission among the population in Owo, Nigeria. The findings suggest that the virus’s spread has been significantly controlled through vaccination programs in the community.