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Anthracycline-induced cardiotoxicity in a child with acute lymphoblastic leukaemia against the background of new coronavirus infection

Gleb V. Kondratiev, M. E. Melnikov,С. А. Кулева, Alexander S. Chepelev,С. Л. Баннова,Tatyana Kornishina, I. A. Reshetnyak, K. D. Murasheva

Voprosy gematologii/onkologii i immunopatologii v pediatrii(2023)

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摘要
Anthracycline chemotherapy drugs are widely used for the treatment of various tumors but they are associated with high cardiotoxicity. The novel coronavirus disease can also negatively affect the heart function. In this article, we report a case of anthracycline-related cardiotoxicity in a child with refractory acute lymphoblastic leukemia and the novel coronavirus disease, describing changes in instrumental and laboratory parameters observed over time during the treatment and providing a description of autopsy samples of the myocardium. The patient’s parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.
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关键词
acute lymphoblastic leukaemia,cardiotoxicity,new coronavirus infection,anthracycline-induced
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