Risk and determinants of low and very low bone mineral density and fractures in a national cohort of Dutch adult childhood cancer survivors (DCCSS-LATER): a cross-sectional study

van Atteveld JE, de Winter DTC,Pluimakers VG,Marta Fiocco, Nievelstein RAJ,Hobbelink MGG, de Vries Ach, Loonen JJ,van Dulmen-den Broeder E, van der Pal Hj,Smf Pluijm,Kremer LCM,Ronckers Cm,van der Heiden-van der Loo M,Versluijs AB,Marloes Louwerens,Dorine Bresters,van Santen Hm, Olsson DS,Imo E. Hoefer, van den Berg SAA,den Hartogh J,Tissing WJE, Neggers SJCMM,van den Heuvel-Eibrink, LATER study group Dutch

Yearbook of pediatric endocrinology（2023）

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Abstract

Brief summary: This Dutch cross-sectional study aimed to assess risk factors for impaired bone mineral density (BMD) and fractures (particularly vertebral fractures) in adult survivors of childhood cancer. The relationships between low BMD (Z-score ≤1), very low BMD (Z-score ≤2), fractures, vertebral fractures, and demographic, treatment-related, endocrine, and lifestyle-related factors was analyzed by logistic regression.

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Key words

bone mineral density,low bone mineral density,fractures,dccss-later,cross-sectional

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