Host-Erythrocytic Sphingosine-1-Phosphate Regulates Plasmodium Histone Deacetylase Activity and Exhibits Epigenetic Control over Cell Death and Differentiation

Raj Kumar Sah,Sakshi Anand,Waseem Dar,Ravi Jain,Geeta Kumari,Evanka Madan,Monika Saini,Aashima Gupta,Nishant Joshi,Rahul Singh Hada,Nutan Gupta,Soumya Pati,Shailja Singh

Microbiology spectrum（2023）

引用 0|浏览6

暂无评分

摘要

Sphingolipid is an 18-carbon amino-alcohol-containing lipid with a sphingosine backbone, which when phosphorylated by sphingosine kinase 1 (SphK-1), generates sphingosine-1-phosphate (S1P), an essential lipid signaling molecule. Dysregulation of S1P function has been observed in a variety of pathologies, including severe malaria.

查看译文

关键词

histone deacetylase activity,exhibits epigenetic control,cell death,host-erythrocytic

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要