The PWVGLS ratio may identify diuretic-naive hypertensive patients at risk for HefPef

The Pulse Wave Velocity-to-Global Longitudinal Strain ratio (PWVGLS ratio) is a sensitive marker that describe and quantify the ventricular–arterial coupling in hypertensive patients. We wanted to know if the PWVGLS ratio can predict an increase in filling pressures in the diuretic-naive hypertensive patient. In all, 38 diuretic naive hypertensive patients and 38 hypertensive patients treated with diuretics were enrolled in the study. The two-dimensional left ventricular global strain where evaluated and the pulse wave velocity with tonometry where performed. Others echocardiographic parameters where mesured: E/E’, left atrial volume, LV mass, the EKG Cornell index and the glomerular filtartion in the two groups. A negative correlation between PWVGLS ratio and EE’ ratio in diuretic-naive hypertensive patients where found with significative Pearson's Correlation Coefficient at 0.41 (significant correlation at the 0.05 level). No significative correlation between PWVGLS ratio and EE’ ratio where found in the treated hypertensive patients. The PWVGLS ratio may assist in decision-making in the treatment of hypertensive patients and in the identification of diuretic-naive hypertensive patients at risk for HFpPEF.