In Vitro Anthelmintic Properties of Euphorbia Milii and Euphorbia Microphylla Linn Extracts

Methanol extracts from the leaves and stems of Euphorbia microphylla Linn and Euphorbia milii were investigated for their activity against Fasciola gigantica, Taenia solium and Pheritima pasthuma, respectively. Five concentrations (10–100mg/ml) of each extract were studied in the bioassay, which involved determination of time of paralysis and time of death of the worms. All the extracts exhibited con-siderable anthelmintic activities, and the order of sensitivity of the extracts to the worms was P. pasthuma > F. gigantica > T. solium. The most active of the extracts were E milii and E microphylla Linn stem methanol extracts. Piperazine citrate (10mg/ml) and distilled water were included in the assay as standard reference drug and control, respectively.