Migraine

Migraine is a neurological pain condition that affects millions of people. It is the most common neurological disease that has significant effects on the brain and consequently on behaviors associated with repeated migraine attacks. The stress of migraine is associated with premigraine, intermigraine, and postmigraine processes. Recent understanding of migraine includes how normally nonpainful stimuli such as light may exacerbate the pain of migraine and how the migraine headache may produce changes in skin sensitivity (allodynia) that can involve the whole body as a marker of central sensitization. Alterations in the brain's function and structure, as revealed by advanced imaging techniques, have provided new insights into the mechanisms and treatments of the disease. Finally, migraine can be studied in the context of multiple stressors (different physiological, psychological, and environmental factors) contributing to abnormal homeostasis or allostatic load.