SUPPLEMENTARY FIGURE 1. Primary CD138+-myeloma cells in bone marrow aspirates express αvβ3/αvβ5 integrins and IGF1R. from Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by Synstatin_IGF1R Inhibits Tumor Growth

Bone marrow aspirates from 12 individual patients were incubated on Sdc1 antibody to capture CD138+ myeloma cells and exclude other cell types present in the aspirates. Captured cells were fixed and stained for αvβ3 (LM609), αvβ5 (P1F6), or IGF1R (JBW902). Stained cells were counted and expressed as a percentage of total captured cells. Data points represent the mean of a minimum of four replicates for each patient.