Significantly Increased Left Ventricular Afterload in Adolescents and Young Adults Conceived through Assisted Reproductive Technologies: Insights from the Munich heARTerY Study

Background: Assisted reproductive technologies (ART) are estimated to facilitate 3 to 6% of births in Germany. In the past, an increased cardiovascular morbidity, including vascular and left ventricular (LV) dysfunction, was suggested within the ART offspring. This study aimed to evaluate whether differences in LV hemodynamics and efficiency can be observed between adolescents/young adults conceived through ART and spontaneously conceived peers by generating noninvasive LV pressure volume loops (PVLs).