Managing hepatocellular carcinoma across the stages: efficacy and outcomes of stereotactic body radiotherapy
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al](2024)
Abstract
Hepatocellular carcinoma (HCC) poses a unique challenge due to its predilection for developing on compromised livers, often limiting surgical options. Stereotactic body radiotherapy (SBRT) has emerged as a promising local treatment modality for HCC. This study aims to assess the effectiveness of SBRT in HCC patients not suitable for surgery, focusing on local control, optimal radiation dosing, and prognostic factors. In this retrospective analysis, 52 HCC patients treated with SBRT were examined. The study assessed local control, progression-free survival (PFS), and overall survival (OS) while conducting dosimetric analyses. The relationship between mean liver dose and Child–Pugh score (CPS) progression was also explored. SBRT demonstrated 93.4
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Key words
Primary liver cancer,Local ablative therapy,Non-invasive oncologic intervention,High-dose radiation therapy,Precision Oncology
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