The Role of Cardiac Magnetic Resonance Imaging in the Evaluation of Malignant Ventricular Arrhythmias in Brugada Syndrome

Brugada syndrome is a genetic disorder associated with an increased risk of sudden cardiac death related to ventricular arrhythmia.1–3 Initial studies reported rates of syncope or sudden cardiac death ranging from 17% to 42%. Although typically considered channelopathy, subtle structural changes have been reported in this disease's histopathology and magnetic resonance imaging. This includes fibrosis, fatty infiltration, and inflammatory infiltrates with collagen deposition.2,4