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Biosynthetic Pathway and Medical Role of Cannabigerolic Acid

Yue Kang, Jian Chi, Yanjie Wang, Xueyong Chi, Quci Zhu, Yuke Zhang,Lingyan Dai

Scholars Journal of Engineering and Technology(2023)

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摘要
Nowadays, the application of cannabinoids in various fields is gradually increasing, and more and more studies have been conducted on cannabigerolic acid, the basic compound produced by cannabis plants, which is produced by the reclamation of olivine acid and isopentenyl catalyzed by cannabis isopentenyl transferase. They are isoprenylated polyketone compounds derived from fatty acids and isoprenoid precursors. They are common receptors for all cannabinoid synthetases and have important effects on the production of cannabinoids. At the same time, CBGA also has certain medicinal value, which has certain efficacy in the treatment of diabetes, and glioblastoma, reducing neuroinflammation of neurodegenerative diseases and treating the side effects of chemotherapy, and will not produce psychotoxic side effects. This paper will describe the synthesis pathway and medical effects of cannabigerolic acid.
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