Reversible tongue atrophy in a patient with acetylcholine receptor antibody-positive myasthenia gravis

Abstract Background Tongue atrophy is an uncommon symptom of myasthenia gravis (MG), especially rare in acetylcholine receptor antibody-positive patients (AchR-MG). Little information could be acquired about its prognosis. Case presentation: Here, we report a case of pronounced tongue atrophy in a 53-year-old AchR-MG man who has been misdiagnosed as myopathy for seven years. After treating with oral corticosteroid and pyridostigmine bromide for 3 months, the tongue volume and the electrophysiological changes restored quickly. Conclusion Our case shows a good prognosis of the tongue atrophy in AchR-MG following correct and timely diagnosis.