Stretching the chains: the destabilizing impact of Cu2+ and Zn2+ ions on K48-linked ubiquitin

Vincenzo Mangini,Giulia Grasso,Benny Danilo Belviso,Michele F.M. Sciacca,Valeria Lanza,Rocco Caliandro,Danilo Milardi

Dalton Transactions（2023）

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摘要

Cu 2+ and Zn 2+ ions play distinct roles in destabilizing the K48-Ub 2 structure, causing separation of the ubiquitin monomers and highlighting their potential to interfere with Ub signalling.

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关键词

ions,zn2+

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