Efficient synthesis of functionalized trifluoromethyl cyclopropanes via cyclopropanation of α-trifluoromethyl styrenes with chloroacetonitrile and ethyl chloroacetate

Yupian Deng, Ying Liu,Jingjing He,Pai Zheng,Sun Zhudi,Song Cao

New Journal of Chemistry（2023）

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摘要

A practical method for the synthesis of functionalized trifluoromethyl cyclopropanes via cyclopropanation of α-trifluoromethyl styrenes with chloroacetonitrile or ethyl chloroacetate was developed.

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关键词

trifluoromethyl cyclopropanes,trifluoromethyl chloroacetate,chloroacetonitrile,cyclopropanation,efficient synthesis

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