"They are closely interconnected, complement each other and pass into each other, there are no clear boundaries between them". Case report

Hereditary angioedema is a rare (1:50,000) hereditary chronic disease from the group of primary immunodeficiencies, which manifests in the form of recurrent skin and mucous membrane edema of the respiratory tract and gastrointestinal tract. Pathogenesis of this disease are associated with an increased risk of a number of cardiovascular pathologies, which is associated with the complexity of management and choosing optimal treatment methods. This case report demonstrates the complexity of managing a patient with hereditary angioedema, multifocal atherosclerosis, severe aortic stenosis, and gastric neuroendocrine cancer.