Impact of cannabis on memory: From in utero to adulthood

The association between cannabis exposure and memory function has been examined in many studies, but it remains difficult to characterize. Reported deficits differ based on a number of methodological and drug use factors. Cannabis exposure occurs in the context of variables that influence its impact on memory, including age and polysubstance use. Methodological factors such as how drug use is reported, differences in periods of abstinence, and the type of memory function assessed also influence the conclusions that can be drawn about the effects of cannabis on memory. Further, the timing, frequency, and dose of cannabis, and whether it is used acutely or chronically are important drug exposure factors associated with memory deficits and cannabis exposure. This review considers the effects of cannabis exposure on memory function from a developmental lens. We review the effects of cannabis exposure on memory following prenatal, adolescent, and adult exposures and then consider how cannabis exposure across the lifespan interacts to impact memory function.