Correction: Assessment of diffuse bone marrow involvement on 18F-fluoro-D-glucose PET/computed tomography
Research Square (Research Square)(2024)
Abstract
This study aims to investigate the role of bone marrow (BM) FDG uptake distribution in assessing pathological status of BM with diffusely increased FDG uptake. We retrospectively analyzed one hundred and thirty-four PET/CT scans with diffusely hypermetabolic BM, which involved forty-nine patients with BM malignant infiltration (BMI) and eighty-five patients with benign BM disorders. The maximum standardized uptake values (SUVmax) of axial skeletons, appendicular skeletons, and the range of humerus FDG uptake were measured. The clinical and laboratory data were collected. Multivariate logistic regression analysis and receiver operating characteristic (ROC) curve were used to evaluate the risk factors for BMI and discriminative ability of above indicators for the pathology status of BM. In patients with diffusely hypermetabolic BM, both the glucose metabolism of axial and appendicular skeletons was higher in BMI than BM benign disorders. The multivariate logistic regression analysis (stepwise) revealed age (odds ratio [OR] 1.073; 95
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Key words
Bone marrow,18F-FDG PET/CT,Hematopoietic malignancies,Autoimmune diseases
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