Enhanced identification and localization of metabolites in Scutellariae Radix using ion mobility enabled MALDI-Q-TOF/MS imaging

Li-Xing Nie,Lieyan Huang,Xiaofei Jia,Shuai Kang,Lingwen Yao, Yue Wu, Hao Yuan,Yongli Liu, Wang Feng, Haiyan Jin,Xiang Li,Shuang‐Cheng Ma

Journal of Pharmaceutical Analysis（2023）

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摘要

• MALDI-IM-MS localization of metabolites in Scutellariae Radix was conducted for the first time. • Mobility- m / z plot offered distinct separation of endogenous metabolites from matrix. • Exclusive trend line enabled more selective characterization of flavonoids.

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关键词

scutellariae radix,maldi-q-tof/ms imaging,metabolites

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