Micro-RNA Landscape of Hepatocellular Carcinoma-Derived Extracellular Vesicles

Jonas Stritzker, Maryam Barsch, P Otto-Mora,Nisha Rana, Tanja Gainey‐Schleicher,Darko Castven,Stefan Tholen, Andreas Blaumeiser,Melanie Börries,Oliver Schilling,J. Marquardt,Robert Thimme,Irina Nazarenko,Bertram Bengsch

Zeitschrift Fur Gastroenterologie（2023）

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摘要

Background Extracellular vesicles (EVs) produced by cancer cells contain bioactive cargo, including micro-RNAs (miRNAs), which can both provide insights into tumor cell communication but may also serve as a biomarker for liquid biopsy. We therefore asked if HCC tumor cell line EVs could be utilized to identify HCC-related patient miRNA profiles in liquid biopsy.

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关键词

micro-rna,carcinoma-derived

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