Synthesis of 5H-chromeno[3,4-c]pyridine derivatives through ruthenium-catalyzed [2 + 2 + 2] cycloaddition

William Parisot,Steve Huvelle,Mansour Haddad,Guillaume Lefèvre,Phannarath Phansavath,Virginie Ratovelomanana‐Vidal

Organic chemistry frontiers（2023）

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摘要

Efficient access to 5 H -chromeno[3,4- c ]pyridines using Ru-catalyzed [2 + 2 + 2] cycloaddition of α,ω-diynes with cyanamides was developed, providing valuable tricyclic pyridine building blocks and enabling access to a biologically relevant intermediate.

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synthesis,ruthenium-catalyzed

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