Characteristics of Exacerbation and Antibiotic Usage in Treatment for Exacerbation of COPD Patients in National Lung Hospital (2022-2023)

Abstract: Exacerbations of COPD are important events in the progression of the disease, being the leading cause of hospitalization and mortality. Bacterial respiratory infections are one of the main causes of exacerbations. This retrospective study was described characteristics of exacerbation and antibiotic use in COPD exacerbation patients hospitalized at the National Lung Hospital. This study included 200 hospitalized patients from January2022 to June 2023. Many patients in the study sample were male (90%), 76% of patients had two or more exacerbations per year. The most isolated bacteria are Haemophilus influenzae, Pseudomonas aeruginosa, Acinetobacter baumannii. There were 77,5% pneumonia patients had Drug Susceptibility Tests (DST), and 54,7% of patients had antibiotic regimens consistent with the DST. The results of this study provide a reliable basis for selecting and improving the effectiveness of antibiotic use in the treatment of COPD exacerbations, improving outcomes and survival prognosis for patients. Keywords: COPD, exacerbation, bacteria, antibiotics.