"Usefulness of the Acute Phase Reactants (APR) Score: Early Detection of Delayed Onset of Sepsis in Extremely Low Birth Weight Infants by APR Score"

The production of acute phase reactants (APRs) in the liver is stimulated by increased inflammatory cytokines. Therefore, inflammatory cytokines are more advantageous than APRs for early diagnosis of neonatal sepsis. There is a machine Latessier TM that can produce results after about 3 minutes with a small amount of sample of 10 μL each at the same time of C-reactive protein (CRP), α1 acid glycoprotein (AGP), and haptoglobin (Hp).