Is Pelvic Exenteration an Option for a Pelvic Recurrence of a Vulvar/Vaginal Melanoma after Previous Radiation Therapy?

Vulvar/vaginal melanomas are uncommon malignancies. Due to the relative infrequency of vulvo-vaginal melanomas, many treatments are used after initial surgical resection. Pelvic radiation may be used in patients who are initially unresectable, have positive lymph nodes or have close margins. Pelvic exenteration after pelvic recurrence of vulvo-vaginal melanomas in a radiated field may be necessary and appropriate in select patients.