456. Altered Temporal Variability of fMRI Signal in 22q11.2 Deletion Syndrome
Biological Psychiatry(2023)
Abstract
22q11.2 Deletion Syndrome (22qDel) is a copy number variant (CNV) in which a hemizygous deletion of ∼46 protein-coding genes from chromosome 22 results in increased risk for schizophrenia and other neuropsychiatric conditions. Studying individuals with 22qDel can provide a powerful framework for linking genes to brain phenotypes and behaviors relevant to these conditions.
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Key words
22q11.2 deletion syndrome, BOLD fMRI signal variability, multi-site imaging data, Psychotic Disorders
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