Front Cover: A Chimeric Peptide Inhibits Red Blood Cell Invasion by Plasmodium falciparum with Hundredfold Increased Efficacy (ChemBioChem 7/2023)**

ChemBioChem(2023)

引用 0|浏览2
暂无评分
摘要
Inhibition of malaria parasite entry into red blood cells by a rationally designed chimeric peptide molecule that exhibits high affinity to parasite protein receptor (AMA1) displayed on the merozoite surface and outcompetes the natural ligand for the receptor (another parasite protein, RON2, embedded on the erythrocyte membrane), resulting in two-digit nanomolar IC50. (Illustrated by Anugraha Ambily). More information can be found in the Research Article by K. Mandal et al.
更多
查看译文
关键词
<i>plasmodium,peptide,blood
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要