Azimuthally Invariant Mueller-Matrix Mapping of Optically Anisotropic Networks of Biological Tissues and Fluids

Experimental investigations of the coordinate distributions of the values of the elements of the Mueller matrices of histological sections of biological tissues were carried out at the location of the Stokes polarimeter. As the main information arrays, we will use the data of analytical modeling a set of values of azimuthally independent Mueller-matrix invariants (MMI). The analysis of the magnitudes of the statistical moments of the first and fourth orders characterizing the distribution of values MMI revealed the maximum average and dispersion values for the Mueller-matrix images of invariants associated with the influence of linear birefringence. The results obtained suggest a fairly high level of balanced accuracy of azimuthally independent Mueller-matrix mapping in the differentiation of changes in the optical anisotropy of benign and malignant tumors of human organs. According to the criteria of evidence-based medicine, the parameter $$R\left( {M_{44} ,\;\Delta M} \right)\ 70\%$$ meets satisfactory quality and $$R\left( {M_{14} ,\;M_{41} } \right)\ 80\%$$ meets good quality. Mueller-matrix mapping of blood-filled biological tissues has proven effective in the differential diagnosis of inflammatory processes of appendicitis tissue—balanced accuracy $$Ac = 78\% - 83\%$$ ).