P303 Real-life data for liver function in children on CFTR-modulators in Bulgaria

Treatment aimed at correcting a specific gene mutation is a completely new approach for CF patients, which is mainly based on the so-called cystic fibrosis protein modulators (CFTR-modulators). These medications have been administered since the end of 2019 to CF patients in Bulgaria as well. Particular attention is directed to liver function in patients on CFTRm, as this may be the limiting factor for these medications.