Supplementary Figure 2 from Vemurafenib Resistance Signature by Proteome Analysis Offers New Strategies and Rational Therapeutic Concepts

Verena Paulitschke,Walter Berger, Philipp Paulitschke, Elisabeth Hofstätter,Bernhard Knapp, Ruth Dingelmaier-Hovorka, Dagmar Födinger,Walter Jäger,Thomas Szekeres,Anastasia Meshcheryakova,Andrea Bileck,Christine Pirker, Hubert Pehamberger,Christopher Gerner,Rainer Kunstfeld

openalex（2023）

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摘要

Proteome characterization of Vemurafenib-sensitive and-resistant melanoma cells V0 and V1 of nuclear fraction. Left: Hierarchical clustering of Z-scored expression values for significantly changed proteins, revealing differences between V0 and V1. Left: Profiles of the five main clusters. Two clusters with the highest difference are selected and the significant regulated groups are depicted. Red: upregulated in V1, green: downregulated in V1.

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vemurafenib resistance signature,proteome analysis

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