Gastrik Intestinal Metaplazi Sıklığı ve Helikobakter Pilori ile İlişkisinin Belirlenmesi

Aim: Gastric intestinal metaplasia (IM) is a precancerous lesion in the pathway to gastric cancer. Helicobacter pylori (HP) is a bacterium that has been associated with an increase in the development of non-cardia gastric cancer and is involved in the development of gastric IM and atrophic gastritis. In this study, we aimed to determine the frequency of IM and its relationship with HP in patients undergoing endoscopic examination with the indication of dyspepsia. Material and Method: The study included 2530 patients who underwent upper gastrointestinal system endoscopy and had gastric biopsy at the Karadeniz Technical University Farabi Hospital Gastroenterology Clinic due to dyspepsia between January 2019 and January 2020. Demographic characteristics of the patients such as age and gender, biopsy findings (presence of IM, HP, atrophy, dysplasia) were evaluated retrospectively. Results: A total of 2530 cases, 1344 (53.1%) women and 1186 (46.9%) men, with a median age of 53 (18-93) years were included in the study. HP was detected in 27.8% of the cases and IM was detected in 26.8%. The median age of 677 patients with positive IM was 59 (19-92) years, and 29.7% (n=352) were male. While no significant difference was found between the sexes in terms of median age within the IM positive and negative groups (p=0.584, p=0.642, respectively), the median age and male sex ratio were higher in patients with IM positive than those with IM negative (p