Chromosome-level genomic assembly and allergome inference reveal novel allergens in the storage mite, Tyrophagus putrescentiae

Tyrophagus putrescentiae is a common storage mite in house dust, stored grains and other food. It has been demonstrated as an important indoor allergen source resulting in IgE-mediated responses and allergic diseases in genetically predisposed patients. Identification and characterization of its allergens using whole genome sequencing is needed for improving allergy diagnostics and developing better immunotherapeutic vaccines.