Perspective Chapter: Multi-Omic Approaches to Vaccine Development against Helminth Diseases

Vrushabh Daga, Evangeline Green,Priyanka Ravichandran,Meagan Short,Meghan May

IntechOpen eBooks(2022)

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Abstract
Though the past three decades have led to a renaissance in vaccine design, the development of vaccines that protect against helminth diseases remains elusive. The need for protective vaccines for humans and livestock remains urgent because of the side-effect profiles of anti-helminthic drugs and the growing incidence of antimicrobial resistance and declining efficacy. The “-omics” era has led to renewed interest in vaccine development against helminth diseases, as candidate vaccines can now be designed, evaluated, and refined in a fraction of the time previously required. In this chapter, we describe and review genomic, transcriptomic, and proteomic approaches to the design of vaccines against helminth diseases.
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Key words
vaccine development,diseases,multi-omic
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