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Convenient multicomponent synthesis of furo[3,2-c]coumarins in the promoting medium DIPEAc and assessment of their therapeutic potential through in silico pharmacophore based target screening

Manisha R. Bhosle, Shabnam M. Shaikh, Vinay Kumar Yadav,Ghanshyam Mali,Giribala M. Bondle, Anil Kumar,Rohan D. Erande, S. Bhattacharyya

New Journal of Chemistry（2022）

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Abstract
A one-pot three-component approach for the synthesis of dihydrofuro[3,2- c ]coumarins was developed via the reaction of aryl/hetryl aldehydes, substituted phenacyl bromides and 4-hydroxycoumarin using N , N -diisopropyl ethyl ammonium acetate as the promoting medium.
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convenient multicomponent synthesis
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